Applications: ADME/Tox

Early detection of compound ADME/Tox issues prevents wasted
resources later on in the drug discovery process. Lead identification projects
often aim to conduct this profiling in parallel with primary screening. One way to do this testing is to implement in vitro assays, with the aim of providing comparable data to more costly in vivo studies. These assays, developed using high throughput principles, can be automated to help drive efficient project progression.

Why Should I Choose HighRes for ADME/Tox?

We have configured example systems to demonstrate the key advantages we offer for ADME/Tox applications.

Click on the system below to find out more!

  • Cytochrome P450 panel screens
  • Membrane potential assays
  • Multiplexed viability and apoptosis assays
  • Intestinal permeability measurements
  • Phospholipidosis screens