|1||x||Pip||Acoustic Dispensing Device|
|1||x||Inc||HighRes SteriStore D|
|1||x||Plt||Automated Plate Washer|
|1||x||Cfg||Automated Plate Centrifuge|
|1||x||Lid||HighRes Lid Valet|
This system is a dual HighRes NanoCell configured for FLIPR assays. This system would typically be used to run low volume calcium mobilisation assays, for identifying compounds with activity against drug discovery targets, such as GPCRs and ion channels. The capabilities include plate washing and low volume dispensing for removal of cell medium and addition of FLIPR dye, a HighRes SteriStore for incubating cell plates, and an acoustic dispenser for direct addition of compounds in DMSO. The workcell is compatible with all common FLIPR assays, including agonist and antagonist formats.
Flexible - Plug in different carts to build the best system for the next experiment. For example, swap out the FLIPR for a multimode reader
Economical - Minimise duplicate equipment purchases - undock the FLIPR for method writing and maintenance, then plug it straight back into the system for automated use
Friendly - Benefit from the intuitive interface of Cellario, HighRes’ scheduling software, making the system easy to use for non-frequent users
Efficient - To get the most out of the system, use Cellario to schedule additional protocols (e.g. cell plating) that can run during overnight periods
HighRes has co-authored a technical note with Molecular Devices on the advantages of using a NanoCell for automated, miniaturized FLIPR screening.