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Liquid handler nest

Liquid Handler Design for High-Density Plate Formats

The push to higher density plate formats in biopharma research has been underway for quite some time, as it is seen as a principle means of reducing the costs of experimentation through higher unit throughput per time slice, and lower reagent volumes per data point. While automated liquid handling technology widely handles 96-well plates with […]

Laboratory Automation Predictions for 2019

Another year is almost in the books, so we thought it would be interesting to lay out some of our expectations for the year ahead. Enjoy! Robotics and automation business cases will be less and less about labor cost savings, and more and more about other benefits such as precision, repeatability and data capture. Labor […]

Lab automation software running on an iMac

Toward the Unification of Laboratory Software Platforms

Scientists are all too familiar with the issues of proliferation of software platforms in their work environments.  Most laboratory devices have their own software packages and interfaces, and the lab as a whole typically runs a variety of additional platforms from lab notebooks, to sample management packages to data analysis software.  In a world in […]

In Memory of Lou Guarracina

Last week, we lost a friend, colleague and source of perpetual inspiration in a tragic and untimely accident.  While he leaves behind friends and family who will miss and mourn him, the passing of HighRes’s founder and Chief Technology Officer Lou Guarracina is also a substantial loss for life science research more generally, where his […]

Why liquid handler decks are so large – it’s a design flaw

How big does the liquid handler deck have to be? This is usually one of the first questions that an automation customer asks their liquid handler salesperson.   The answer that usually comes back is that larger decks offer multiple benefits, such as: More flexibility: Bigger decks mean more accessories on deck, and more pipetting/gripper arms […]

The Future of Lab Automation Requires Enterprise Thinking

From startups to the largest biopharma research organizations, we have the great fortune of being in and out of tons of different labs across the globe. As a result, we also see commonalities and differences in how companies approach the specification and deployment of automation technology in their enterprises. If there is one thing that […]

Large Molecule Research: Higher Targeting Efficiencies Still Leave Room for Automation

The rise of biopharmaceuticals has evolved research paradigms and continues to displace use of traditional small molecule therapies in the market. Biologics are forecast to account for more than half of the Top 100 selling drugs by 2022, up from roughly one-third in 2012. Driving these therapies to market has required significant investment in upfront […]

Machine Learning and Drug Discovery

Yesterday, Recursion Pharmaceuticals announced that the Food and Drug Administration had cleared their investigational new drug application for a Phase 1 clinical trial in the treatment of cerebral cavernous malformation (CCM). While this is certainly good news for treating this rare genetic disease, it is also an important milestone in the use of machine learning […]

How AI is Transforming Drug Discovery

Bringing a new pharmaceutical drug to market takes about 12 years and can reach into the billions in R&D expenditures, industry leaders are now seeking more efficient methods of approaching this process and AI is emerging as a potential solution. The interest in AI-driven solutions for early stage drug discovery is growing steadily among biopharma […]

Are You Considering a DIY Automation Project?

With so many automation components available and seemingly simple, it can be tempting to skip working with an integrator and launch into the project on your own. Considering a “Do it Yourself” automation project? With so many automation components available and seemingly simple, it can be tempting to skip working with an integrator and launch […]